Valentine Nfonsam

Professor - Tucson


Valentine N. Nfonsam, MD, MS, FACS, FASCRS is an Associate Professor, Surgery; Interim Chief, Division of Surgical Oncology; and Program Director for the General Surgery Residency Program at the University of Arizona. His clinical specialties are colorectal and gastrointestinal surgery, geriatric surgical oncology and laparoscopic/robotic-assisted surgery. A graduate of the University of Illinois College of Medicine in Chicago, Dr. Nfonsam Started his Surgery residency at UT southwestern, In Dallas and completed his training at North Shore-Long Island Jewish Health System in New York. During his residency, he completed a minimally invasive surgery (MIS) research fellowship at Cleveland Clinic. Dr. Nfonsam came to the University of Arizona from the University of South Florida, Tampa, where he completed a two-year fellowship in colon and rectal surgery.

Dr. Nfonsam’s research focuses on colorectal cancer, especially in young patients. His research also focuses on cancer and overall health disparities. In the last several years, his lab has concentrated on the biology of early onset colorectal cancer; contributing factors and carcinogenesis. He also has a deep interest in colorectal cancer biomarkers. Dr. Nfonsam’s long-term goal is to continue to establish the scientific foundation for targeted treatment for early onset colorectal cancer.


Selected Publications

Nfonsam, V. N., L. E. Nfonsam, D. Chen, P. N. Omesiete, A. Cruz, R. B. Runyan, and J. Jandova, "COMP Gene Coexpresses With EMT Genes and Is Associated With Poor Survival in Colon Cancer Patients.", J Surg Res, vol. 233, pp. 297-303, 2019 Jan. PMID: 30502262

Nfonsam, V., W. Xu, J. Koblinski, and J. Jandova, "Gene Expression Analysis of Sporadic Early-Onset Rectal Adenocarcinoma.", Gastrointest Cancer (Jersey City), vol. 1, issue 1, 2016. PMCID: PMC5321608  PMID: 28239680

Jandova, J., W. Xu, and V. Nfonsam, "Sporadic early-onset colon cancer expresses unique molecular features.", J Surg Res, vol. 204, issue 1, pp. 251-60, 2016 07. PMID: 27451894

Bernstein, C., V. Nfonsam, A. Ramarao Prasad, and H. Bernstein, "Epigenetic field defects in progression to cancer.", World J Gastrointest Oncol, vol. 5, issue 3, pp. 43-9, 2013 Mar 15. PMCID: PMC3648662  PMID: 23671730

Davis, D. M., J. E. Marcet, J. C. Frattini, A. D. Prather, J. J. L. Mateka, and V. N. Nfonsam, "Is it time to lower the recommended screening age for colorectal cancer?", J Am Coll Surg, vol. 213, issue 3, pp. 352-61, 2011 Sep. PMID: 21737316


UArizona Profile:

Cancer Center Profile:

Department of Surgery Profile:

NCBI Bibliography:

Research Interests: 
Cancer Biology and Cancer Prevention
Molecular medicine