Dr. Ledford’s current work in the area of pulmonary surfactant immunobiology combines her knowledge of mouse genetics, pulmonary disease models and immune function regulation and focuses on understanding the role of Surfactant Protein-A (SP-A) and how it regulates signaling pathways within various immune cell populations. Specifically, she is interested in how SP-A regulates degranulation, either directly or indirectly, of two important cell types in asthma: mast cells and eosinophils. More recently, Dr. Ledford’s research has focused on understanding how genetic variation within human SP-A2 alters functionality of the protein in relation to eosinophil activities and how this translates to characteristics observed in human asthma.
- Ph.D. Genetics and Molecular Biology
University of North Carolina at Chapel Hill, Chapel Hill, North Carolina, United States
Determining the Role of Onzin in Immunity.
- B.S. Genetics
University of Georgia, Athens, Georgia, United States
Assistant Professor (2015-present), University of AZ, Tucson, AZ
Assistant Research Professor (2011-2014), Duke University, Durham, NC
- Eureka Certificate in Translational Medicine
Eureka Institute for Translational Medicine, Spring 2017
- Jo Rae Wright Award for Outstanding Science
American Thoracic Society, Spring 2012