The study of stem cells, particularly in the context of the nervous system, is an area whose pursuit has significant implications for understanding how the brain is built and works but also how it ages and responds to disease. Comprehending the regenerative potential of stem cells also has direct relevance in developing curative or preventative treatments for age-related neurodegenerative diseases, such as Parkinson’s disease (PD), that are currently non-existent. We use cutting-edge stem cell technologies to advance knowledge on age-related neurodegeneration, and develop early diagnostics and therapeutics for PD. Moreover, our work, although mostly focused on PD, has broad implications across several other age-related neurodegenerative disorders.
Madhavan Lab: https://madhavanlab.medicine.arizona.edu
Research profile on Center for Innovation in Brain Science site: https://www.cibs.uahs.arizona.edu/madhavaninv