Nathan Cherrington

Professor - Tucson

Associate Dean, Research and Graduate Studies, College of Pharmacy
Director, Southwest Environmental Health Science Center
Director, Center for Toxicology
Professor, Pharmacology and Toxicology
1885 Society Distinguished Scholar

Nathan Cherrington, PhD, ATS, associate dean, research and graduate studies and professor, Pharmacology and Toxicology—directs graduate studies for the University of Arizona’s College of Pharmacy and NIEHS P30 Southwest Environmental Health Sciences Center. He also serves as interim director, Arizona Board of Regents Center for Toxicology and professor, Mel & Enid Zuckerman College of Public Health, University of Arizona.

Author of more than 200 journal articles and abstracts about metabolic expression, especially related to liver damage, Cherrington sits on several editorial boards. The 1885 Society Distinguished Scholar and Fellow, Academy of Toxicological Sciences received 19 grants and holds two patents.

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Research Interests: 

  • Adverse drug reaction
  • Drug metabolism and distribution
  • Gene expression/polymorphisms
  • Phenoconversion
  • Hepatic and renal ontogeny
  • Non-alcoholic steatohepatitis

Education: 

          Postdoc, Toxicology, University of Kansas Medical Center, 2002
          PhD, Toxicology, North Carolina State University, 1997
          BS, Zoology, Brigham Young University (Provo, Utah), 1993

Select Publications

2018

Dzierlenga, A. L., and N. J. Cherrington, "Misregulation of membrane trafficking processes in human nonalcoholic steatohepatitis.", J Biochem Mol Toxicol, vol. 32, issue 3, pp. e22035, 2018 Mar. PMCID: PMC5854531  PMID: 29341352

Li, H., E. Toth, and N. J. Cherrington, "Alcohol Metabolism in the Progression of Human Nonalcoholic Steatohepatitis.", Toxicol Sci, vol. 164, issue 2, pp. 428-438, 2018 Aug 01.

Li, H., E. Toth, and N. J. Cherrington, "Asking the Right Questions With Animal Models: Methionine- and Choline-Deficient Model in Predicting Adverse Drug Reactions in Human NASH.", Toxicol Sci, vol. 161, issue 1, pp. 23-33, 2018 Jan 01.

2017

Li, H., M. J. Canet, J. D. Clarke, D. Billheimer, S. A. Xanthakos, J. E. Lavine, R. P. Erickson, and N. J. Cherrington, "Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis.", Drug Metab Dispos, vol. 45, issue 12, pp. 1317-1325, 2017 12. PMCID: PMC5697442  PMID: 28986475

Lee, S., S. Kim, S. Hwang, N. J. Cherrington, and D-Y. Ryu, "Dysregulated expression of proteins associated with ER stress, autophagy and apoptosis in tissues from nonalcoholic fatty liver disease.", Oncotarget, vol. 8, issue 38, pp. 63370-63381, 2017 Sep 08. PMCID: PMC5609929 

 

520-626-0219
Research Interests: 
Drug discovery
Genetics
Pharmacology
Precision medicine
Toxicology