Associate Dean, Research and Graduate Studies, College of Pharmacy
Director, Southwest Environmental Health Science Center
Director, Center for Toxicology
Professor, Pharmacology and Toxicology
1885 Society Distinguished Scholar
Nathan Cherrington, PhD, ATS, associate dean, research and graduate studies and professor, Pharmacology and Toxicology—directs graduate studies for the University of Arizona’s College of Pharmacy and NIEHS P30 Southwest Environmental Health Sciences Center. He also serves as interim director, Arizona Board of Regents Center for Toxicology and professor, Mel & Enid Zuckerman College of Public Health, University of Arizona.
Author of more than 200 journal articles and abstracts about metabolic expression, especially related to liver damage, Cherrington sits on several editorial boards. The 1885 Society Distinguished Scholar and Fellow, Academy of Toxicological Sciences received 19 grants and holds two patents.
Research Interests:
- Adverse drug reaction
- Drug metabolism and distribution
- Gene expression/polymorphisms
- Phenoconversion
- Hepatic and renal ontogeny
- Non-alcoholic steatohepatitis
Education:
Postdoc, Toxicology, University of Kansas Medical Center, 2002
PhD, Toxicology, North Carolina State University, 1997
BS, Zoology, Brigham Young University (Provo, Utah), 1993
Select Publications
2018
Dzierlenga, A. L., and N. J. Cherrington, "Misregulation of membrane trafficking processes in human nonalcoholic steatohepatitis.", J Biochem Mol Toxicol, vol. 32, issue 3, pp. e22035, 2018 Mar. PMCID: PMC5854531 PMID: 29341352
Li, H., E. Toth, and N. J. Cherrington, "Alcohol Metabolism in the Progression of Human Nonalcoholic Steatohepatitis.", Toxicol Sci, vol. 164, issue 2, pp. 428-438, 2018 Aug 01.
Li, H., E. Toth, and N. J. Cherrington, "Asking the Right Questions With Animal Models: Methionine- and Choline-Deficient Model in Predicting Adverse Drug Reactions in Human NASH.", Toxicol Sci, vol. 161, issue 1, pp. 23-33, 2018 Jan 01.
2017
Li, H., M. J. Canet, J. D. Clarke, D. Billheimer, S. A. Xanthakos, J. E. Lavine, R. P. Erickson, and N. J. Cherrington, "Pediatric Cytochrome P450 Activity Alterations in Nonalcoholic Steatohepatitis.", Drug Metab Dispos, vol. 45, issue 12, pp. 1317-1325, 2017 12. PMCID: PMC5697442 PMID: 28986475
Lee, S., S. Kim, S. Hwang, N. J. Cherrington, and D-Y. Ryu, "Dysregulated expression of proteins associated with ER stress, autophagy and apoptosis in tissues from nonalcoholic fatty liver disease.", Oncotarget, vol. 8, issue 38, pp. 63370-63381, 2017 Sep 08. PMCID: PMC5609929