Education
Postdoctoral: Cardiovascular Pharmacology/Physiology, Université de Montreal, 2003 – 2008.
PhD: Department of Pharmacology, Queen's University, 2003.
Publications
Biwer LA, D’Souza KM, Abidali A, Tu D, Hale TM. Time Course of Cardiac Inflammation During Nitric Oxide Synthase Inhibition in SHR: Impact of Prior Transient ACE Inhibition. Hypertension Research; 2016:39(1)8-18
D’Souza KM, Biwer LA, Madhavpeddi L, Ramaiah P, Shahid W, Biwer LA, Hale TM. Persistent Change in Cardiac Fibroblast Physiology Following Transient ACE Inhibition. American Journal of Physiology – Heart and Circulatory Physiology; 2015;309(8):H1346-53.
Der Sarkissian S, Tea BS, Touyz RM, Deblois D, Hale TM. Role of angiotensin II type 2 receptor during regression of cardiac hypertrophy in spontaneously hypertensive rats. Journal of the American Society of Hypertension; 2013; 7(2):118-27.
Biwer LA, Broderick TL, Xu H, Carroll C, Hale TM. Short-Term ACE Inhibition Produces Long-Term Protection Against NOS Inhibitor-Induced Cardiac Dysfunction. Acta Physiologica; 2013;207(1):156-65
Hale TM, Hannan JL, Carrier S, deBlois D, Adams MA. Targeting Vascular Structure for the Treatment of Sexual Dysfunction. Journal of Sexual Medicine; 2009; 6(Suppl 3):210-20.
For a complete listing of Dr. Hale's publications, search PubMed.
Research Areas
Hypertension, cardiovascular disease, sexual dysfunction
Research Summary
The Hale lab investigates the mechanisms involved in the pathological remodeling of the heart, vasculature and erectile tissue that underlie heart failure and sexual dysfunction. In addition, we are examining the role that prenatal stress plays in predisposing individuals to cardiovascular disease and sexual dysfunction in adulthood. The long-term goal of our work is to develop novel therapeutic strategies for the treatment of these two conditions.